Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722181 | 1.00 | GAA (0.43) | GAAHTR3ABACE1CNR2PDE10A | |
| SCHEMBL28722001 | 0.83 | GAA (0.49) | GAAHTR3ABACE1ADRB1HRH3 | |
| SCHEMBL29495994 | 0.83 | GAA (0.49) | GAAHTR3ABACE1ADRB1HRH3 | |
| SCHEMBL28722866 | 0.79 | GAA (0.68) | GAAHTR3ABACE1 | |
| SCHEMBL3299921 | 0.79 | HTR3A (0.58) | GAAHTR3ABACE1ADRB1 | |
| SCHEMBL29495981 | 0.79 | GAA (0.68) | GAAHTR3ABACE1 | |
| SCHEMBL17619976 | 0.76 | GRIN2D (0.50) | HTR3ACNR2PDE10ATRPV3 | |
| SCHEMBL30642980 | 0.76 | GRIN2D (0.50) | HTR3ACNR2PDE10ATRPV3 | |
| SCHEMBL29496052 | 0.74 | GAA (0.62) | GAAHTR3ABACE1CNR2PDE10A | |
| SCHEMBL28722011 | 0.74 | GAA (0.62) | GAAHTR3ABACE1CNR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |