Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 6/20 | 1.00 |
| ▸ | AHCY | P23526 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | PI4KA | P42356 | 3/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393316 | 1.00 | ADORA2A (1.00) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL5810639 | 1.00 | ADORA2A (1.00) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL904363 | 1.00 | ADORA2A (1.00) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL28855667 | 0.98 | ADORA2A (0.97) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL16603993 | 0.87 | AHCY (0.85) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL12620928 | 0.87 | ADORA2A (0.77) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL8815696 | 0.86 | ADORA2A (0.75) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL6040056 | 0.86 | ADORA2A (0.75) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL25861 | 0.86 | ADORA2A (0.75) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL16504492 | 0.85 | ADORA2A (0.74) | ADORA2AADORA1AHCYALDH1A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731988-B | Total synthesis ketoreductase and preparation method using same | 重庆普佑生物医药有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-114574454-B | Short-chain dehydrogenase, mutant and application thereof | 沈阳药科大学 | 2023-11-17 | — | — | CN | claimed |
| CN-112626144-B | Biosynthesis method of tenofovir intermediate (R) -9- (2-hydroxypropyl) adenine | 江苏阿尔法药业股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-110530997-B | Method for detecting 9- (2-hydroxypropyl) adenine enantiomer | 湖北丽益医药科技有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-116332934-B | Tenofovir intermediate Synthesis process of intermediate | 江苏阿尔法药业股份有限公司 | 2025-08-26 | — | — | CN | disclosed |
| CN-120483983-A | Preparation method of tenofovir intermediate R- (+) -9- (2-hydroxypropyl) adenine | 乐平市赛复乐医药化工有限公司 | 2025-08-15 | — | — | CN | disclosed |
| CN-120483983-A | Preparation method of tenofovir intermediate R- (+) -9- (2-hydroxypropyl) adenine | 乐平市赛复乐医药化工有限公司 | 2025-08-15 | — | — | CN | disclosed |
| CN-116731988-B | Total synthesis ketoreductase and preparation method using same | 重庆普佑生物医药有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116731988-B | Total synthesis ketoreductase and preparation method using same | 重庆普佑生物医药有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114574454-B | Short-chain dehydrogenase, mutant and application thereof | 沈阳药科大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-116854735-A | Synthesis method of tenofovir | 广西奕安泰药业有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116731988-A | Total synthesis ketoreductase and preparation method using same | 重庆普佑生物医药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116332934-A | Synthesis process of tenofovir intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112626144-B | Biosynthesis method of tenofovir intermediate (R) -9- (2-hydroxypropyl) adenine | 江苏阿尔法药业股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-112626144-B | Biosynthesis method of tenofovir intermediate (R) -9- (2-hydroxypropyl) adenine | 江苏阿尔法药业股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-112626144-B | Biosynthesis method of tenofovir intermediate (R) -9- (2-hydroxypropyl) adenine | 江苏阿尔法药业股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-114574454-A | Short-chain dehydrogenase and mutant and application thereof | 沈阳药科大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-110530997-B | Method for detecting 9- (2-hydroxypropyl) adenine enantiomer | 湖北丽益医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-110530997-B | Method for detecting 9- (2-hydroxypropyl) adenine enantiomer | 湖北丽益医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-110530997-B | Method for detecting 9- (2-hydroxypropyl) adenine enantiomer | 湖北丽益医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |