Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 6/20 | 1.00 |
| ▸ | AHCY | P23526 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | PI4KA | P42356 | 3/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496348 | 1.00 | ADORA2A (1.00) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL1393316 | 1.00 | ADORA2A (1.00) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL904363 | 1.00 | ADORA2A (1.00) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL28855667 | 0.98 | ADORA2A (0.97) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL16603993 | 0.87 | AHCY (0.85) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL12620928 | 0.87 | ADORA2A (0.77) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL8815696 | 0.86 | ADORA2A (0.75) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL6040056 | 0.86 | ADORA2A (0.75) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL25861 | 0.86 | ADORA2A (0.75) | ADORA2AADORA1AHCYALDH1A1PI4KA | |
| SCHEMBL16504492 | 0.85 | ADORA2A (0.74) | ADORA2AADORA1AHCYALDH1A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110530997-B | Method for detecting 9- (2-hydroxypropyl) adenine enantiomer | 湖北丽益医药科技有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-110530997-A | The detection method of 9- (2- hydroxypropyl) adenine enantiomer | HUBEI LIVSCIEN PHARM SCI & TECH CO LTD | 2019-12-03 | — | — | CN | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-110530997-B | Method for detecting 9- (2-hydroxypropyl) adenine enantiomer | 湖北丽益医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-110530997-A | The detection method of 9- (2- hydroxypropyl) adenine enantiomer | HUBEI LIVSCIEN PHARM SCI & TECH CO LTD | 2019-12-03 | — | — | CN | disclosed |
| EP-2682397-B1 | Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same | GILEAD SCIENCES INC (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2006114492-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE HYDROXYPROPYLENED ADENINE | SHASUN PHARMA SOLUTIONS LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
| US-6653296-B1 | 2-phosphonomethoxypropyl derivatives of purine and pyrimidine bases | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2003-11-25 | — | — | US | disclosed |
| US-6479673-B1 | Antiretroviral enantiomeric nucleotide analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2002-11-12 | — | — | US | disclosed |
| US-6057305-A | Antiretroviral enantiomeric nucleotide analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2000-05-02 | — | — | US | disclosed |
| EP-0654037-B1 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1999-05-12 | — | — | EP | disclosed |
| EP-0654037-A1 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003467-A2 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1994-02-17 | — | — | WO | disclosed |