Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 12/20 | 0.43 |
| ▸ | CALCR | P30988 | 12/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.41 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496498 | 0.98 | RAMP3 (0.45) | RAMP3CALCRAPLNRCALCRLRAMP1 | |
| SCHEMBL29496437 | 0.95 | PLK1 (0.43) | RAMP3CALCRAPLNRCALCRLRAMP1 | |
| SCHEMBL29823805 | 0.94 | RAMP3 (0.39) | RAMP3CALCRAPLNRPLK1 | |
| SCHEMBL29823809 | 0.93 | RAMP3 (0.45) | RAMP3CALCRAPLNRPLK1 | |
| SCHEMBL29496489 | 0.92 | PLK1 (0.45) | RAMP3CALCRAPLNRPLK1 | |
| SCHEMBL29496452 | 0.91 | PLK1 (0.44) | RAMP3CALCRPLK1 | |
| SCHEMBL30385468 | 0.88 | NRP1 (0.43) | APLNRPLK1 | |
| SCHEMBL30745234 | 0.87 | GRB2 (0.42) | RAMP3CALCRAPLNRPLK1 | |
| SCHEMBL29496455 | 0.87 | RAMP3 (0.46) | RAMP3CALCREPHA2 | |
| SCHEMBL29496425 | 0.87 | RAMP3 (0.49) | RAMP3CALCRPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220235111-A1 | Variant Single-Chain Insulin Analogues | CASE WESTERN RESERVE UNIVERSITY | 2022-07-28 | — | — | US | disclosed |
| EP-3969467-A2 | VARIANT SINGLE-CHAIN INSULIN ANALOGUES | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-03-23 | — | — | EP | disclosed |