Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.57 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.56 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.56 |
| ▸ | MC4R | P32245 | 2/20 | 0.55 |
| ▸ | MC5R | P33032 | 2/20 | 0.55 |
| ▸ | MC3R | P41968 | 2/20 | 0.55 |
| ▸ | MC1R | Q01726 | 2/20 | 0.55 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.55 |
| ▸ | CALCR | P30988 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | TFPI | P10646 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678292 | 0.95 | KEAP1 (0.58) | KEAP1IL23RNMUR2NMUR1EPHA2 | |
| SCHEMBL29627571 | 0.94 | KEAP1 (0.59) | KEAP1IL23RNMUR2NMUR1RAMP3 | |
| SCHEMBL30061928 | 0.93 | IL23R (0.61) | KEAP1IL23RNMUR2NMUR1RAMP3 | |
| SCHEMBL29730557 | 0.92 | SLC6A2 (0.59) | KEAP1IL23RNMUR2NMUR1OPRM1 | |
| SCHEMBL30558096 | 0.91 | SLC6A2 (0.60) | IL23RNMUR2NMUR1EPHA2OPRM1 | |
| SCHEMBL29678305 | 0.91 | IL23R (0.59) | KEAP1IL23RNMUR2NMUR1MC4R | |
| SCHEMBL31119607 | 0.89 | IL23R (0.54) | KEAP1IL23RNMUR2NMUR1RAMP3 | |
| SCHEMBL30558098 | 0.89 | SLC6A2 (0.67) | OPRM1OPRD1SLC6A2 | |
| SCHEMBL31622475 | 0.88 | C5AR1 (0.67) | KEAP1MC4RMC5RMC3RMC1R | |
| SCHEMBL31119609 | 0.87 | APLNR (0.55) | KEAP1IL23RNMUR2NMUR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110339369-B | Improved process for preparing physiologically active polypeptide complexes | 韩美科学株式会社 | 2024-01-23 | — | — | CN | disclosed |
| EP-4178440-A1 | KITS AND METHODS FOR MEASURING INSULIN SENSATIVITY | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2023-05-17 | — | — | EP | disclosed |
| WO-2022173807-A2 | CONFORMATIONALLY CONSTRAINED GLUCAGON ANALOGUES AND THEIR USE IN GLUCAGON-SINGLE CHAIN INSULIN FUSION PROTEINS | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-08-18 | — | — | WO | disclosed |
| EP-3969467-A2 | VARIANT SINGLE-CHAIN INSULIN ANALOGUES | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-03-23 | — | — | EP | disclosed |