Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17883795 | 0.78 | CYP11B2 (0.47) | KITHTR2BHTR6GRM2 | |
| SCHEMBL13749911 | 0.77 | ATM (0.52) | KIT | |
| SCHEMBL17896626 | 0.77 | HTR2B (0.67) | KITHTR2BHTR6 | |
| SCHEMBL22507230 | 0.76 | MEN1 (0.54) | KITGRM2 | |
| SCHEMBL167098 | 0.76 | MEN1 (0.57) | KITHTR2BHTR6AGPAT2 | |
| SCHEMBL3536604 | 0.75 | ITK (0.46) | TRPA1GRM2AGPAT2 | |
| SCHEMBL3542531 | 0.75 | ITK (0.43) | TRPA1HTR2BHTR6GRM2AGPAT2 | |
| SCHEMBL169462 | 0.74 | SYK (0.47) | KITHTR2BHTR6S1PR1AGPAT2 | |
| SCHEMBL13476855 | 0.74 | ATM (0.50) | F11ALOX12 | |
| SCHEMBL10175602 | 0.74 | HTR2B (0.51) | KITHTR2BHTR6AGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022092180-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE THEREOF | 日本農薬株式会社 | 2022-05-05 | — | — | WO | disclosed |