Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498550 | 1.00 | MAPT (0.46) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL19989321 | 1.00 | MAPT (0.46) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL19994859 | 1.00 | MAPT (0.46) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL19989317 | 1.00 | MAPT (0.46) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL19989270 | 0.84 | TDO2 (0.49) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL19989513 | 0.84 | TDO2 (0.49) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL29859576 | 0.84 | TDO2 (0.49) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL29859224 | 0.84 | ALDH1A1 (0.50) | MAPTHSD17B10POLBMCOLN3TDO2 | |
| SCHEMBL29859221 | 0.84 | TDO2 (0.49) | MAPTHSD17B10AKR1C3POLBMCOLN3 | |
| SCHEMBL19989448 | 0.84 | ALDH1A1 (0.50) | MAPTHSD17B10POLBMCOLN3TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715608-B | Indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-109715629-B | Aza-indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |