SCHEMBL29499092

SCHEMBL29499092

C[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 3/20 0.68
▸ ECE1 P42892 12/20 0.63
▸ ERAP2 Q6P179 1/20 0.62
▸ ALOX15 P16050 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696985 0.96 ACE (0.65) ACEECE1ERAP2ALOX15
SCHEMBL31696723 0.94 ACE (0.60) ACEECE1ERAP2
SCHEMBL29488096 0.94 ACE (0.60) ACEECE1ERAP2
SCHEMBL29536181 0.93 ACE (0.69) ACEECE1ERAP2ALOX15
SCHEMBL30051087 0.92 ACE (0.75) ACEECE1ERAP2ALOX15
SCHEMBL9235805 0.92 ACE (0.78) ACEECE1ALOX15
SCHEMBL2488765 0.92 ACE (0.78) ACEECE1ALOX15
SCHEMBL1228369 0.92 ACE (0.78) ACEECE1ALOX15
SCHEMBL9235801 0.92 ACE (0.78) ACEECE1ALOX15
SCHEMBL29400177 0.92 ACE (0.78) ACEECE1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578345-B2 Single molecule peptide sequencing BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-17 — — US disclosed
US-12379381-B2 Single molecule peptide sequencing BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-08-05 — — US disclosed
US-20240302380-A1 SINGLE MOLECULE PEPTIDE SEQUENCING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-09-12 — — US disclosed
US-20240272146-A1 CHROMOGENIC AND FLUOROGENIC COMPOUNDS AND THEIR USE FOR BIOLOGICAL DETECTION AAT BIOQUEST, INC. 2024-08-15 — — US disclosed
US-20230107647-A1 SINGLE MOLECULE PEPTIDE SEQUENCING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-04-06 — — US disclosed
US-11435358-B2 Single molecule peptide sequencing BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-09-06 — — US disclosed
US-20220091130-A1 SINGLE MOLECULE PEPTIDE SEQUENCING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2022-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230107647-A1 SINGLE MOLECULE PEPTIDE SEQUENCING QPCTL, ANPEP, VIP ACE 1689/4885ECE1 1401/4885ERAP2 831/4885
US-11435358-B2 Single molecule peptide sequencing QPCTL, ANPEP, VIP ACE 1717/4885ECE1 1371/4885ERAP2 842/4885
US-12379381-B2 Single molecule peptide sequencing MICA, ANPEP, DNPEP ACE 3263/4885ECE1 1286/4885ERAP2 1026/4885
US-12578345-B2 Single molecule peptide sequencing SET, PTMS, MICA ACE 2836/4885ECE1 3977/4885ERAP2 2803/4885
US-20240272146-A1 CHROMOGENIC AND FLUOROGENIC COMPOUNDS AND THEIR USE FOR BIOLOGICAL DETECTION ANTXR2, CDYL, VIP ACE 297/4885ECE1 543/4885ERAP2 671/4885
US-20240302380-A1 SINGLE MOLECULE PEPTIDE SEQUENCING QPCTL, ANPEP, VIP ACE 1689/4885ECE1 1401/4885ERAP2 831/4885
US-20220091130-A1 SINGLE MOLECULE PEPTIDE SEQUENCING QPCTL, ANPEP, VIP ACE 1689/4885ECE1 1401/4885ERAP2 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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