SCHEMBL29696985

SCHEMBL29696985

C[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(N)=O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.65
▸ ECE1 P42892 12/20 0.60
▸ GHSR Q92847 1/20 0.59
▸ ERAP2 Q6P179 1/20 0.58
▸ ALOX15 P16050 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29488096 0.96 ACE (0.60) ACEECE1GHSRERAP2
SCHEMBL31344343 0.96 GHSR (0.65) ACEECE1GHSR
SCHEMBL29499092 0.96 ACE (0.68) ACEECE1ERAP2ALOX15
SCHEMBL31696723 0.94 ACE (0.60) ACEECE1GHSRERAP2
SCHEMBL30051087 0.92 ACE (0.75) ACEECE1ERAP2ALOX15
SCHEMBL10865665 0.92 ERAP2 (0.64) ACEECE1GHSRERAP2
SCHEMBL30834729 0.91 ACE (0.61) ACEECE1ERAP2ALOX15
SCHEMBL1228369 0.90 ACE (0.78) ACEECE1ALOX15
SCHEMBL9235801 0.90 ACE (0.78) ACEECE1ALOX15
SCHEMBL9235805 0.90 ACE (0.78) ACEECE1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 — — US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 ACE 3899/4885ECE1 1368/4885GHSR 3695/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 ACE 3899/4885ECE1 1368/4885GHSR 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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