Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22614051 | 0.86 | KMT2A (0.43) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL29408862 | 0.86 | KMT2A (0.43) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL22614357 | 0.82 | HSD11B1 (0.42) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL29409182 | 0.81 | POLB (0.46) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL22613977 | 0.81 | POLB (0.46) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL27470804 | 0.81 | KDM1A (0.40) | KDM1AMAOAMAOBKMT2AGNRHR | |
| SCHEMBL29408993 | 0.77 | HSD11B1 (0.42) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL30971615 | 0.76 | KDM1A (0.43) | KDM1AMAOAMAOBBACE1KMT2A | |
| SCHEMBL29499487 | 0.75 | HPGD (0.47) | KDM1AMAOAMAOBKMT2ANPC1 | |
| SCHEMBL14562254 | 0.74 | KMT2A (0.49) | KDM1AMAOAMAOBBACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206848-A | Substituted cycloalkyl compounds as modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-03-18 | — | — | CN | disclosed |