Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409098 | 1.00 | GSK3B (0.35) | GSK3BDYRK1AIDO1MCHR1GPR119 | |
| SCHEMBL29499492 | 0.88 | GSK3B (0.37) | GSK3BDYRK1AIDO1GPR119ATF4 | |
| SCHEMBL29409171 | 0.88 | GSK3B (0.37) | GSK3BDYRK1AIDO1GPR119ATF4 | |
| SCHEMBL22614435 | 0.86 | MCHR1 (0.36) | IDO1MCHR1EP300KCNH2TRPA1 | |
| SCHEMBL29408978 | 0.80 | DRD2 (0.40) | GSK3BDYRK1AATF4DPP8DPP9 | |
| SCHEMBL29409165 | 0.77 | ATF4 (0.42) | GSK3BDYRK1AIDO1ATF4DPP8 | |
| SCHEMBL29409148 | 0.75 | PIK3CA (0.37) | MCHR1EP300KCNH2 | |
| SCHEMBL22613986 | 0.75 | PIK3CA (0.37) | MCHR1EP300KCNH2 | |
| SCHEMBL29409021 | 0.74 | DPP8 (0.37) | GSK3BDYRK1AIDO1DPP8DPP9 | |
| SCHEMBL29409153 | 0.74 | NR1H4 (0.36) | IDO1GPR119ATF4TRPA1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206848-A | Substituted cycloalkyl compounds as modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-03-18 | — | — | CN | disclosed |