Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tilorone SCHEMBL352401 | 1.00 | MAPT (1.00) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL30520073 | 1.00 | MAPT (1.00) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL30882955 | 0.98 | MAPT (0.97) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL30002597 | 0.98 | MAPT (0.97) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL11257327 | 0.98 | MAPT (0.97) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL146373 | 0.98 | MAPT (0.97) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL30882954 | 0.98 | MAPT (0.97) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL3701437 | 0.98 | MAPT (0.97) | MAPTKMT2ACHRNA7POLBHTT | |
| SCHEMBL146374 | 0.97 | MAPT (0.94) | MAPTKMT2ACHRNA7POLBHTT | |
| Tilorone SCHEMBL28965494 | 0.97 | MAPT (0.94) | MAPTKMT2ACHRNA7POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118175999-A | Process for the preparation of 2, 7-dihydroxy-9-fluorenone useful for the synthesis of telulone and its salts | 科学与工业研究委员会 | 2024-06-11 | — | — | CN | claimed |
| CN-114469913-B | Use of Tilorone for preventing/treating African swine fever virus infection | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 2024-03-22 | — | — | CN | claimed |
| WO-2023067624-A1 | A PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-04-27 | — | — | WO | claimed |
| CN-114469913-A | Application of Tilorone in preventing/treating African swine fever virus infection | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 2022-05-13 | — | — | CN | claimed |
| CN-118175999-A | Process for the preparation of 2, 7-dihydroxy-9-fluorenone useful for the synthesis of telulone and its salts | 科学与工业研究委员会 | 2024-06-11 | — | — | CN | disclosed |
| CN-114469913-B | Use of Tilorone for preventing/treating African swine fever virus infection | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 2024-03-22 | — | — | CN | disclosed |
| WO-2023067624-A1 | A PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-04-27 | — | — | WO | disclosed |
| CN-114469913-A | Application of Tilorone in preventing/treating African swine fever virus infection | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 2022-05-13 | — | — | CN | disclosed |
| WO-2022081905-A1 | VIRAL VACCINE COMPOSITIONS FOR INOCULATING A SUBJECT AGAINST A CORONAVIRUS, AN INFLUENZA VIRUS, OR BOTH | ATOSSA THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |