Tilorone

Tilorone

SCHEMBL352401

CCN(CC)CCOc1ccc2c(c1)C(=O)c1cc(OCCN(CC)CC)ccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 1.00
KMT2A Q03164 3/20 1.00
CHRNA7 P36544 1/20 1.00
POLB P06746 1/20 0.65
HTT P42858 1/20 0.65
SMARCA2 P51531 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
MEN1 O00255 1/20 0.57
NPC1 O15118 1/20 0.57
ALDH1A1 P00352 1/20 0.57
GAA P10253 1/20 0.57
RAB9A P51151 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tilorone SCHEMBL30520073 1.00 MAPT (1.00) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL29500271 1.00 MAPT (1.00) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL30882955 0.98 MAPT (0.97) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL30002597 0.98 MAPT (0.97) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL11257327 0.98 MAPT (0.97) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL146373 0.98 MAPT (0.97) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL30882954 0.98 MAPT (0.97) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL3701437 0.98 MAPT (0.97) MAPTKMT2ACHRNA7POLBHTT
SCHEMBL146374 0.97 MAPT (0.94) MAPTKMT2ACHRNA7POLBHTT
Tilorone SCHEMBL28965494 0.97 MAPT (0.94) MAPTKMT2ACHRNA7POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1098 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137806-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2026-05-21 US claimed
US-12458622-B2 Methods of treatment of coronavirus-induced inflammation conditions THE GENERAL HOSPITAL CORPORATION (US) 2025-11-04 US claimed
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
WO-2025137577-A1 SHORT VIRAL RNAS (SVRNAS) WITH THERAGNOSTIC POTENTIAL IN INFECTION WITH SARS-COV-2 AND RELATED VIRUSES THE JOHNS HOPKINS UNIVERSITY (US) 2025-06-26 WO claimed
US-20250186623-A1 EXPRESSION SYSTEM FOR THE TREATMENT OF CANCER FUNDACION PARA LA INVESTIGACION MEDICA APLICADA (ES) 2025-06-12 US claimed
US-20250188143-A1 COMBINED GENE AND RADIO THERAPY FOR THE TREATMENT OF CANCER FUNDACION PARA LA INVESTIGACION MEDICA APLICADA (ES) 2025-06-12 US claimed
WO-2025097070-A1 ORAL DOSAGE FORM WITH CATIONICALLY CHARGEABLE HYDROGEL FOR DELIVERY OF ACTIVE AGENT ENTREGA INC. (US) 2025-05-08 WO claimed
US-20250134850-A1 PLANT-DERIVED SMALL MOLECULES AS MARBURG VIRUS INHIBITORS BAJRAI LEENA HUSSEIN (SA) 2025-05-01 US claimed
EP-4525855-A1 INTERCALATING SUGAR MOLECULES Xalud Therapeutics, Inc. (US) 2025-03-26 EP claimed
US-20250057819-A1 DRUG COMBINATIONS FOR INHIBITING CORONAVIRUS REPLICATION INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2025-02-20 US claimed
US-6080383-A Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic agents into radioactive toxic precipitates in the cancer ROSE SAMUEL (US) 2000-06-27 US claimed
WO-2000025787-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME GUILFORD PHARMACEUTICALS INC. (US) 2000-05-11 WO claimed
US-5816259-A Method for the diagnosis and treatment of cancer by the accumulation of radioactive precipitates in targeted cells ROSE SAMUEL (US) 1998-10-06 US claimed
WO-1998030247-A1 A METHOD AND COMPOSITION FOR CANCER TREATMENT BY ENZYMATIC CONVERSION OF SOLUBLE RADIOACTIVE TOXIC AGENTS ROSE SAMUEL (US) 1998-07-16 WO claimed
EP-0316440-B1 System and method for providing localized Mössbauer absorption in an organic medium MILLS RANDELL L (US) 1996-01-03 EP claimed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO claimed
US-4455142-A Method of coadministering an antigen and an immunopotentiator ALZA CORPORATION (US) 1984-06-19 US claimed
US-3947593-A ANTIVIRUL AGENTS RICHARDSON-MERRELL INC. (US) 1976-03-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 MAPT 1647/4885KMT2A 1760/4885CHRNA7 83/4885
US-12458622-B2 Methods of treatment of coronavirus-induced inflammation conditions C3AR1, IL5, IL4 MAPT 4050/4885KMT2A 4447/4885CHRNA7 1726/4885
US-20250057819-A1 DRUG COMBINATIONS FOR INHIBITING CORONAVIRUS REPLICATION MME, ACE, ACE2 MAPT 1710/4885KMT2A 4251/4885CHRNA7 483/4885
US-20260137806-A1 INTERCALATING SUGAR MOLECULES SLC2A1, SLC2A2, SLC2A4 MAPT 4591/4885KMT2A 3581/4885CHRNA7 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.