Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501050 | 0.92 | TGFBR1 (0.54) | TGFBR1IRAK4 | |
| SCHEMBL29501083 | 0.80 | TGFBR1 (0.38) | TGFBR1IRAK4 | |
| SCHEMBL25335330 | 0.79 | TGFBR1 (0.49) | TGFBR1IRAK4KDM4EEPHB3 | |
| SCHEMBL25333943 | 0.75 | TGFBR1 (0.46) | TGFBR1IRAK4KDM4EEPHB3 | |
| SCHEMBL25942896 | 0.71 | TGFBR1 (0.52) | TGFBR1IRAK4 | |
| SCHEMBL25942659 | 0.71 | TGFBR1 (0.54) | TGFBR1IRAK4 | |
| SCHEMBL25943030 | 0.71 | TGFBR1 (0.54) | TGFBR1IRAK4 | |
| SCHEMBL25338468 | 0.71 | TGFBR1 (0.61) | TGFBR1IRAK4 | |
| SCHEMBL25942937 | 0.70 | TGFBR1 (0.41) | TGFBR1IRAK4EPHB3 | |
| SCHEMBL25943032 | 0.70 | TGFBR1 (0.51) | TGFBR1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380818-A | Pyrazolo pyridine compound, and pharmaceutical composition, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-04-22 | — | — | CN | disclosed |