Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950419 | 0.81 | BDKRB1 (0.38) | BDKRB1GRIN2BHIF1A | |
| SCHEMBL2950173 | 0.81 | BDKRB1 (0.45) | BDKRB1HIF1A | |
| SCHEMBL2945817 | 0.76 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL2946447 | 0.73 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL13213911 | 0.73 | BDKRB1 (0.69) | BDKRB1 | |
| SCHEMBL2951908 | 0.72 | BDKRB1 (0.48) | BDKRB1GRIN2B | |
| SCHEMBL3032923 | 0.72 | BDKRB1 (0.58) | BDKRB1 | |
| SCHEMBL2946726 | 0.71 | BDKRB1 (0.42) | BDKRB1GRIN2BHIF1A | |
| SCHEMBL2941734 | 0.69 | HIF1A (0.35) | BDKRB1GRIN2BHIF1A | |
| SCHEMBL2940943 | 0.68 | BDKRB1 (0.40) | BDKRB1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |