Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13213911 | 0.82 | BDKRB1 (0.69) | BDKRB1 | |
| SCHEMBL2947679 | 0.81 | BDKRB1 (0.70) | BDKRB1 | |
| SCHEMBL2940943 | 0.74 | BDKRB1 (0.40) | BDKRB1GRIN2B | |
| SCHEMBL2950173 | 0.73 | BDKRB1 (0.45) | BDKRB1 | |
| SCHEMBL2950171 | 0.72 | BDKRB1 (0.39) | BDKRB1GRIN2B | |
| SCHEMBL2950419 | 0.70 | BDKRB1 (0.38) | BDKRB1GRIN2B | |
| SCHEMBL2946726 | 0.69 | BDKRB1 (0.42) | BDKRB1GRIN2B | |
| SCHEMBL2950422 | 0.66 | HIF1A (0.41) | BDKRB1 | |
| SCHEMBL2946447 | 0.66 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL2941734 | 0.64 | HIF1A (0.35) | BDKRB1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |