Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 10/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 7/20 | 0.49 |
| ▸ | SIRT7 | Q9NRC8 | 3/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32668275 | 0.80 | GRB2 (0.47) | SIRT2SIRT1SIRT3IDE | |
| SCHEMBL32668279 | 0.79 | GRB2 (0.44) | SIRT2SIRT1SIRT3IDE | |
| SCHEMBL29501818 | 0.79 | SIRT2 (0.46) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL29501829 | 0.79 | SIRT2 (0.55) | SIRT2SIRT1SIRT3SIRT5SIRT7 | |
| SCHEMBL32668260 | 0.75 | KLHL20 (0.44) | SIRT2SIRT1SIRT3IDE | |
| SCHEMBL16615623 | 0.71 | SIRT2 (0.42) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL10751453 | 0.69 | GLI1 (0.42) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL24808654 | 0.69 | IDE (0.70) | IDE | |
| SCHEMBL14374129 | 0.68 | GLI1 (0.44) | SIRT2SIRT1SIRT3SIRT5 | |
| Proline SCHEMBL11591714 | 0.67 | KLK7 (0.43) | MMP1MMP9ADAM17IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3989997-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | Washington University (US) | 2022-05-04 | — | — | EP | disclosed |