SCHEMBL295030

SCHEMBL295030

C=CC(=O)C(C=Cc1ccccc1)=C(C)C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
PLIN1 O60240 2/20 0.43
RECQL P46063 2/20 0.43
PLIN5 Q00G26 2/20 0.43
ABHD5 Q8WTS1 2/20 0.43
TNKS O95271 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5402625 0.75 GLA (0.47) GLATDP1LMNAMAPTALDH1A1
SCHEMBL5608238 0.75 MAPT (0.44) GLATDP1LMNAMAPTALDH1A1
SCHEMBL1404410 0.74 GLA (0.52) GLATDP1LMNAMAPTALDH1A1
SCHEMBL2474967 0.73 MAPT (0.59) GLATDP1LMNAMAPTALDH1A1
Butenone SCHEMBL10919130 0.73 GLA (0.72) GLATDP1LMNAMAPTALDH1A1
SCHEMBL4171114 0.73 MAPT (0.46) GLATDP1LMNAMAPTALDH1A1
SCHEMBL353086 0.72 GLA (0.42) GLATDP1LMNAMAPTALDH1A1
SCHEMBL11119689 0.71 MAPT (0.55) GLATDP1LMNAMAPTALDH1A1
Butenone SCHEMBL28533337 0.71 GLA (0.81) GLATDP1LMNAMAPTALDH1A1
Acrylonitrile SCHEMBL2549054 0.70 MAPT (0.60) GLATDP1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991643-B1 USE OF POLYNUCLEAR PHENOLIC COMPOUNDS AS STABILISERS BASF SE (DE) 2019-10-30 EP disclosed
EP-1268426-B1 4-FORMYL AMINO-N-METHYLPIPERIDINE DERIVATIVES, THE USE THEREOF AS STABILISERS AND ORGANIC MATERIAL STABILISED THEREWITH BASF SE (DE) 2013-09-18 EP disclosed
EP-2215156-B1 LIQUID STABILIZER MIXTURE BASF SE (DE) 2013-01-09 EP disclosed
EP-2450400-A2 Stabilisers for inanimate organic materials BASF SE (DE) 2012-05-09 EP disclosed
EP-2239258-B1 Tetrahydrobenzoxazines BASF SE (DE) 2012-03-14 EP disclosed
EP-2318454-B1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2012-02-29 EP disclosed
EP-2318454-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2011-05-11 EP disclosed
EP-2272821-A2 Trinuclear phenolic compounds BASF SE (DE) 2011-01-12 EP disclosed
EP-2267104-A2 Use of polynuclear phenolic compounds as dispersants BASF SE (DE) 2010-12-29 EP disclosed
EP-2185641-B1 STABILIZER MIXTURE BASF SE (DE) 2010-12-29 EP disclosed
EP-0272591-A2 Acetylene diurea derivatives and their use to stabilize plastics BASF Aktiengesellschaft (DE) 1988-06-29 EP disclosed
EP-0272588-A1 Acetylene diurea derivatives and their use in stabilizing synthetic resins BASF Aktiengesellschaft (DE) 1988-06-29 EP disclosed
EP-0213570-A2 Glycolurile derivatives and their use as polymer stabilizers BASF Aktiengesellschaft (DE) 1987-03-11 EP disclosed
EP-0207396-A1 Tetrahydrofurancarboxylic-acid derivatives BASF Aktiengesellschaft (DE) 1987-01-07 EP disclosed
EP-0057160-B1 2-(2-HYDROXYPHENYL)-BENZOTRIAZOLES, THEIR USE AS ULTRAVIOLET STABILIZERS AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0022079-B1 POLYALKYLPIPERIDYL UREAS, THEIR APPLICATION AS STABILIZERS AND POLYMERS THUS STABILIZED CIBA-GEIGY AG (CH) 1984-01-18 EP disclosed
EP-0059168-A1 Organic elastomers and mineral and synthetic lubricating oils containing phenolmercaptocarboxylic esters as stabilizers CIBA-GEIGY AG (CH) 1982-09-01 EP disclosed
EP-0057160-A1 2-(2-Hydroxyphenyl)-benzotriazoles, their use as ultraviolet stabilizers and their preparation CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed
EP-0042358-A1 Organic sulphides and their use as stabilizers in organic materials CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed
EP-0022079-A1 Polyalkylpiperidyl ureas, their application as stabilizers and polymers thus stabilized CIBA-GEIGY AG (CH) 1981-01-07 EP disclosed