SCHEMBL29503115

SCHEMBL29503115

Oc1ccc2cccc3c2c1CC=C3.Oc1ccc2cccc3c2c1CC=C3.Oc1ccc2cccc3c2c1CC=C3.[Nd+3]

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.36
CYP3A4 P08684 2/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18695361 0.77 CYP3A4 (0.34) CYP3A4TSHRALDH1A1CYP1A1CYP1A2
SCHEMBL28408506 0.77 TSHR (0.34) CYP3A4TSHRALDH1A1CYP1A1CYP1A2
SCHEMBL276579 0.75 BCL2L1 (0.39) CDK2CYP3A4TSHRALDH1A1CYP1A2
SCHEMBL2881023 0.74 CYP3A4 (0.35) CDK2CYP3A4TSHR
SCHEMBL27664477 0.74 BCL2L1 (0.38) CDK2CYP3A4TSHRALDH1A1HPGD
SCHEMBL28418486 0.73 ALDH1A1 (0.31) CYP3A4TSHRALDH1A1CYP1A1CYP1A2
Catechol SCHEMBL28946741 0.72 CYP2D6 (0.38) CDK2CYP3A4TSHRALDH1A1CYP1A2
SCHEMBL9880000 0.71 TSHR (0.39) CYP3A4TSHRALDH1A1CYP1A2HPGD
SCHEMBL31126656 0.71
Pyrene SCHEMBL21060519 0.71 CYP3A4 (0.45) CYP3A4TSHRALDH1A1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108569995-B Platinum complex and device thereof 香港大学 2022-03-25 CN disclosed