Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276579 | 0.98 | BCL2L1 (0.39) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9304448 | 0.77 | BCL2L1 (0.36) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6749423 | 0.77 | BCL2L1 (0.41) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL29503115 | 0.74 | CDK2 (0.36) | ALDH1A1HSD17B10HPGDCDK2CYP3A4 | |
| SCHEMBL276578 | 0.73 | SLC6A2 (0.35) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL972273 | 0.72 | ALDH1A1 (0.35) | ALDH1A1ALOX15HSD17B10TDP1LMNA | |
| SCHEMBL3784850 | 0.71 | CYP1A2 (0.35) | ALDH1A1TDP1LMNARECQLSLC6A2 | |
| SCHEMBL11662214 | 0.71 | CYP3A4 (0.35) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL8765141 | 0.71 | SLC6A2 (0.34) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL2974474 | 0.71 | TRPA1 (0.36) | SLC6A2HTR2ASLC6A4HRH1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287705-A | Synthesis of 1 alpha-fluoro-25-hydroxy-16-23E-diene-26, 27-bishomo-20-epi-cholecalciferol | BIOXELL SPA (IT) | 2008-10-15 | — | — | CN | claimed |
| CN-101522199-A | Novel method of treatment of male sub-fertility | BIOXELL SPA (IT) | 2009-09-02 | — | — | CN | disclosed |
| CN-101287705-A | Synthesis of 1 alpha-fluoro-25-hydroxy-16-23E-diene-26, 27-bishomo-20-epi-cholecalciferol | BIOXELL SPA (IT) | 2008-10-15 | — | — | CN | disclosed |
| CN-1953752-A | Treatment of interstitial cystitis with vitamin D compounds | BIOXELL SPA (IT) | 2007-04-25 | — | — | CN | disclosed |
| CN-1886140-A | Methods for treating bladder dysfunction | BIOXELL SPA (IT) | 2006-12-27 | — | — | CN | disclosed |