Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL440459 | 0.93 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL10449623 | 0.93 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL8214834 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL28924405 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL37647 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL30253568 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL3083 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL7085968 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL1450484 | 0.87 | NFKB1 (0.36) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL23633140 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534489-B2 | Ionic solid | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2026-01-27 | — | — | US | claimed |
| US-20220135607-A1 | IONIC SOLID | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2022-05-05 | — | — | US | claimed |
| US-12534489-B2 | Ionic solid | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2026-01-27 | — | — | US | disclosed |
| EP-4650469-A1 | PROCESS FOR ELECTROMEDIATED METAL STRIPPING AND RECOVERY | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 2025-11-19 | — | — | EP | disclosed |
| US-20250230555-A1 | VANADIUM-DOPED MANGANESE COBALT SPINEL OXIDE BASED ELECTROCATALYSTS FOR GENERATING HYDROGEN | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-07-17 | — | — | US | disclosed |
| US-12312628-B2 | Metabolic control over organometallic catalysts using electroactive bacteria | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-05-27 | — | — | US | disclosed |
| CN-118595580-A | Working face manufacturing method and device based on shock wave coupling field dimension reduction guide control | 贵州华科铝材料工程技术研究有限公司 | 2024-09-06 | — | — | CN | disclosed |
| US-20240261770-A1 | COBALT CATALYSTS CONTAINING \"SMART\" OR \"TASK SPECIFIC\" ANIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2024-08-08 | — | — | US | disclosed |
| US-11860084-B2 | Quantitative auxiliary-free chirality sensing with a metal probe | GEORGETOWN UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2022256525-A1 | COBALT CATALYSTS CONTAINING \"SMART\"OR\"TASK SPECIFIC\"ANIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2022-12-08 | — | — | WO | disclosed |
| CN-110165048-B | Transition metal oxide resistive switching device with doped buffer | 塞姆特里克斯内存有限公司 | 2022-11-01 | — | — | CN | disclosed |
| US-20220135607-A1 | IONIC SOLID | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2022-05-05 | — | — | US | disclosed |
| US-20220113247-A1 | QUANTITATIVE AUXILIARY-FREE CHIRALITY SENSING WITH A METAL PROBE | GEORGETOWN UNIVERSITY | 2022-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534489-B2 | Ionic solid | ADH1C, ADM2, SLC2A1 | NFKB1 1535/4885TSHR 2905/4885CA12 95/4885 |
| US-20220135607-A1 | IONIC SOLID | NUP160, NUP188, NUP210 | NFKB1 3262/4885TSHR 4492/4885CA12 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.