Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | P4HB | P07237 | 2/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475844 | 0.90 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4EHSD17B10ACHE | |
| SCHEMBL2950856 | 0.81 | ACHE (0.51) | ALDH1A1L3MBTL1KDM4EHSD17B10ACHE | |
| SCHEMBL2950474 | 0.77 | KDM4E (0.53) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL25384511 | 0.77 | ACHE (0.47) | ALDH1A1L3MBTL1KDM4EHSD17B10ACHE | |
| SCHEMBL6073275 | 0.76 | DPP4 (0.42) | ALDH1A1SMN1; SMN2TP53THRBP2RX7 | |
| SCHEMBL11383249 | 0.75 | SLC6A2 (0.49) | ALDH1A1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3311700 | 0.73 | MAPT (0.55) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL3316437 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL14775491 | 0.71 | ACHE (0.55) | ALDH1A1L3MBTL1KDM4EHSD17B10ACHE | |
| SCHEMBL14775127 | 0.71 | SLC6A2 (0.66) | ALDH1A1L3MBTL1KDM4EACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |