Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506236 | 1.00 | MAPT (0.46) | MAPTLMNACA12CA1CA9 | |
| SCHEMBL276699 | 1.00 | MAPT (0.46) | MAPTLMNACA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL22092050 | 0.98 | MAPT (0.44) | MAPTLMNACA12CA1CA9 | |
| SCHEMBL27333832 | 0.98 | MAPT (0.44) | MAPTLMNACA12CA1CA9 | |
| Trifluoroacetic Acid SCHEMBL16059014 | 0.85 | MAPT (0.38) | MAPTLMNAMCL1RAB9ANPC1 | |
| SCHEMBL27899495 | 0.82 | MAPT (0.34) | MAPTLMNACA12CA1CA9 | |
| SCHEMBL21832239 | 0.74 | NPC1 (0.45) | MAPTLMNACA12CA9TDP1 | |
| SCHEMBL27922678 | 0.74 | RAB9A (0.41) | MAPTLMNATDP1RAB9ANPC1 | |
| SCHEMBL31345781 | 0.72 | NCOA1 (0.66) | MAPTLMNACA12CA1CA9 | |
| SCHEMBL2019537 | 0.72 | NCOA1 (0.66) | MAPTLMNACA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679423-B | Amination reagent and synthesis method and application thereof | 中南大学 | 2022-04-26 | — | — | CN | claimed |
| CN-112679423-B | Amination reagent and synthesis method and application thereof | 中南大学 | 2022-04-26 | — | — | CN | disclosed |