SCHEMBL29506643

SCHEMBL29506643

CCOC(=O)C1=C(C)NC(=O)NC1c1ccc2ccccc2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
KIF11 P52732 1/20 0.69
GAA P10253 2/20 0.64
HSD17B10 Q99714 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.62
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
ADORA2B P29275 3/20 0.61
MAPK1 P28482 2/20 0.61
TSHR P16473 2/20 0.61
POLB P06746 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
TP53 P04637 1/20 0.61
KMT2A Q03164 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14413867 1.00 ALDH1A1 (0.70) ALDH1A1KIF11GAAHSD17B10L3MBTL1
SCHEMBL19752615 1.00 ALDH1A1 (0.70) ALDH1A1KIF11GAAHSD17B10L3MBTL1
SCHEMBL13420122 0.88 CTDSP1 (0.67) ALDH1A1KIF11GAAL3MBTL1ADORA2B
SCHEMBL19752617 0.86 ALDH1A1 (0.53) ALDH1A1KIF11GAAHSD17B10POLB
SCHEMBL5347891 0.85 KIF11 (0.75) KIF11HSD17B10CA12CA1CA2
SCHEMBL19752667 0.85 KIF11 (0.75) KIF11HSD17B10CA12CA1CA2
SCHEMBL18025267 0.85 KIF11 (0.75) KIF11HSD17B10CA12CA1CA2
SCHEMBL19732961 0.84 USP2 (0.58) ALDH1A1GAAHSD17B10L3MBTL1TSHR
SCHEMBL10279779 0.84 USP2 (0.58) ALDH1A1GAAHSD17B10L3MBTL1TSHR
SCHEMBL5340534 0.83 KIF11 (0.80) ALDH1A1KIF11GAAHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437100-B Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex 山西医科大学 2022-03-11 CN disclosed