Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HRH2 | P25021 | 1/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749239 | 1.00 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22761517 | 1.00 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22749238 | 1.00 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL13770893 | 0.90 | TLR7 (0.65) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22761521 | 0.88 | TLR7 (0.60) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22761539 | 0.88 | TLR7 (0.60) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22761522 | 0.88 | TLR7 (0.60) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL29508376 | 0.88 | TLR7 (0.60) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL4670100 | 0.86 | TLR7 (0.61) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL10588025 | 0.86 | TLR7 (0.61) | TLR7ADORA2ALMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |