SCHEMBL29508489

SCHEMBL29508489

COC(=O)c1cc(Cl)cc(CBr)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
HPGD P15428 2/20 0.46
XBP1 P17861 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
YTHDC1 Q96MU7 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
LMNA P02545 3/20 0.43
KDM4E B2RXH2 3/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979331 1.00 ALDH1A1 (0.46) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL4652534 0.87 CA12 (0.52) ALDH1A1HPGDCA12CA1CA2
SCHEMBL455338 0.87 CA12 (0.52) ALDH1A1MAPTHPGDCA12CA1
SCHEMBL23032499 0.86 ALDH1A1 (0.49) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL3639909 0.84 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL30546399 0.84 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL7013307 0.84 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL16528649 0.83 CYP4F2 (0.54) MEN1MAPTKMT2ACA12CA1
SCHEMBL18614935 0.81 ALDH1A1 (0.45) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL16186346 0.81 ALDH1A1 (0.45) ALDH1A1MEN1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551839-B Heteroaryl-triazole compounds as pesticides 拜耳公司 2024-06-04 CN disclosed
CN-115551839-A Heteroaryl-triazole compounds as pesticides 拜耳公司 2022-12-30 CN disclosed
CN-114286820-A Enzyme inhibitors 卡尔维斯塔制药有限公司 2022-04-05 CN disclosed