SCHEMBL7013307

SCHEMBL7013307

COC(=O)c1cc(Cl)cc(CCl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 2/20 0.47
XBP1 P17861 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
YTHDC1 Q96MU7 1/20 0.45
LMNA P02545 3/20 0.44
KDM4E B2RXH2 3/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3639909 0.89 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL30546399 0.89 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL762808 0.89 CA12 (0.52) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL30045106 0.88 RAPGEF3 (0.41) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL23032499 0.87 ALDH1A1 (0.49) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL8979331 0.84 ALDH1A1 (0.46) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL29508489 0.84 ALDH1A1 (0.46) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL16186346 0.83 ALDH1A1 (0.45) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL18614935 0.83 ALDH1A1 (0.45) ALDH1A1MEN1MAPTKMT2AHPGD
SCHEMBL67540 0.82 ALDH1A1 (0.62) ALDH1A1MEN1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551839-B Heteroaryl-triazole compounds as pesticides 拜耳公司 2024-06-04 CN disclosed
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-18 US disclosed
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-18 US disclosed
CN-115551839-A Heteroaryl-triazole compounds as pesticides 拜耳公司 2022-12-30 CN disclosed
EP-0889034-B1 AMINOPYRIDINE DERIVATIVES BANYU PHARMA CO LTD (JP) 2003-09-17 EP disclosed
US-6011039-A USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-01-04 US disclosed
EP-0889034-A1 AMINOPYRIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES PRXL2A, GLRX3, CYP4F3 ALDH1A1 4213/4885MEN1 3891/4885MAPT 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.