SCHEMBL29508672

SCHEMBL29508672

Cn1c2ccccc2c2cc(N(c3ccccc3)c3ccc4cc(Br)ccc4c3)ccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ACHE P22303 2/20 0.41
GPR3 P46089 1/20 0.41
TSPO P30536 2/20 0.40
BCHE P06276 1/20 0.39
PABPC1 P11940 1/20 0.37
CYP2A6 P11509 1/20 0.37
MCL1 Q07820 1/20 0.36
PTGER4 P35408 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23660743 1.00 MAPT (0.43) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL28533770 0.90 L3MBTL1 (0.56) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL18565019 0.89 KDM4E (0.48) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL23660606 0.87 KDM4E (0.46) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL12559383 0.86 GPR3 (0.55) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL12249804 0.86 GPR3 (0.55) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL17740714 0.86 L3MBTL1 (0.45) MAPTKDM4EALDH1A1MEN1HTT
SCHEMBL13241977 0.84 KDM4E (0.38) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL18565020 0.82 MAPT (0.43) MAPTKDM4EALDH1A1MEN1HPGD
SCHEMBL18565024 0.82 MAPT (0.43) MAPTKDM4EALDH1A1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233676-B High-performance hole transport material and preparation and application thereof 华南理工大学 2022-03-29 CN disclosed