Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LIPC | P11150 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22750386 | 1.00 | ALOX5 (0.67) | ALOX5GRM5SNRNP200MAOBDDB1 | |
| SCHEMBL14280129 | 0.86 | ALOX5 (0.53) | ALOX5MAOBDDB1CRBNMAOA | |
| SCHEMBL3977885 | 0.85 | ALOX5 (0.59) | ALOX5GRM5SNRNP200MAOBMAOA | |
| SCHEMBL4444307 | 0.84 | ALOX5 (0.51) | ALOX5GRM5SNRNP200MAOBDDB1 | |
| SCHEMBL5737605 | 0.82 | GRM5 (0.59) | ALOX5GRM5SNRNP200MAOBDDB1 | |
| SCHEMBL9645227 | 0.81 | ALOX5 (1.00) | ALOX5GRM5 | |
| SCHEMBL8915218 | 0.80 | FFAR4 (0.46) | ALOX5L3MBTL1 | |
| SCHEMBL4434062 | 0.79 | ALOX5 (0.46) | ALOX5GRM5SNRNP200MAOB | |
| SCHEMBL13097411 | 0.78 | GRM5 (0.56) | ALOX5GRM5SNRNP200MAOBDDB1 | |
| SCHEMBL13097167 | 0.77 | GRM5 (0.54) | ALOX5GRM5SNRNP200MAOBDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974013-A | Pyrrolidine compounds | 伊莱利利公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-3980409-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2022-04-13 | — | — | EP | disclosed |
| CN-114008021-A | Pyrrolidine compounds | 伊莱利利公司 | 2022-02-01 | — | — | CN | disclosed |