Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709992 | 1.00 | AR (0.44) | ARKDM4EMEN1MAPTKMT2A | |
| SCHEMBL17711502 | 0.85 | AR (0.41) | ARKDM4EMEN1MAPTKMT2A | |
| SCHEMBL17711243 | 0.85 | AR (0.41) | ARKDM4EMEN1MAPTKMT2A | |
| SCHEMBL17716654 | 0.79 | AR (0.43) | AR | |
| SCHEMBL17711374 | 0.78 | AR (0.60) | ARNR1H2NR1H3RORC | |
| SCHEMBL19600777 | 0.78 | AR (0.49) | ARKDM4EMEN1MAPTKMT2A | |
| SCHEMBL20428942 | 0.76 | AR (0.51) | ARKDM4EMEN1MAPTKMT2A | |
| SCHEMBL17711466 | 0.73 | MEN1 (0.37) | ARKDM4EMEN1MAPTKMT2A | |
| SCHEMBL19606079 | 0.72 | AR (0.44) | ARMEN1KMT2AHSD17B10KCNJ11 | |
| SCHEMBL17711245 | 0.71 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064224-B | Amide-substituted thiazoles as modulators of Ror gamma t | 詹森药业有限公司 | 2022-03-29 | — | — | CN | disclosed |