Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19600777 | 0.77 | AR (0.49) | ARRORCNR1H2NR1H3MEN1 | |
| SCHEMBL20428942 | 0.76 | AR (0.51) | ARRORCNR1H2NR1H3MLYCD | |
| SCHEMBL21028351 | 0.74 | KCNJ11 (0.54) | KCNJ11ABCC9ABCC8KCNJ8MEN1 | |
| SCHEMBL12658946 | 0.73 | CTRC (0.48) | — | |
| SCHEMBL17709992 | 0.72 | AR (0.44) | ARRORCNR1H2NR1H3KCNJ11 | |
| SCHEMBL29509660 | 0.72 | AR (0.44) | ARRORCNR1H2NR1H3KCNJ11 | |
| SCHEMBL23773113 | 0.66 | P2RX7 (0.40) | TSHR | |
| SCHEMBL9710259 | 0.66 | CLCN2 (0.43) | MEN1TSHRKMT2A | |
| SCHEMBL29509453 | 0.66 | PDK2 (0.46) | ARRORCNR1H2NR1H3KCNJ11 | |
| SCHEMBL17711502 | 0.66 | AR (0.41) | ARNR1H2NR1H3KCNJ11ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327492-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327492-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | RORA, RORC, RORB | AR 757/4885RORC 2/4885NR1H2 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.