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SCHEMBL29510574

SCHEMBL29510574

CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](N)CC(N)=O)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@H](CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.62
▸ CALCR P30988 4/20 0.58
▸ CRHR1 P34998 1/20 0.54
▸ CRHR2 Q13324 1/20 0.54
▸ AGTR1 P30556 1/20 0.52
▸ AGTR2 P50052 1/20 0.52
▸ NTSR2 O95665 1/20 0.50
▸ NTSR1 P30989 1/20 0.50
▸ ANPEP P15144 1/20 0.50
▸ LNPEP Q9UIQ6 1/20 0.50
▸ APLNR P35414 1/20 0.50
▸ OPRM1 P35372 1/20 0.49
▸ OPRD1 P41143 1/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ NMBR P28336 1/20 0.49
▸ GRPR P30550 1/20 0.49
▸ NMUR2 Q9GZQ4 1/20 0.48
▸ NMUR1 Q9HB89 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29793680 0.98 F2 (0.64) F2CALCRCRHR1CRHR2AGTR1
SCHEMBL29510563 0.90 NTSR2 (0.58) AGTR1AGTR2NTSR2NTSR1
SCHEMBL29467322 0.90 OPRD1 (0.56) NTSR2NTSR1OPRM1OPRD1OPRK1
SCHEMBL30176423 0.86 CALCR (0.68) F2CALCRCRHR1CRHR2
SCHEMBL30504147 0.86 F2 (0.67) F2CALCRCRHR1CRHR2NTSR2
SCHEMBL30504145 0.86 F2 (0.67) F2CALCRCRHR1CRHR2NTSR2
SCHEMBL30504153 0.86 F2 (0.67) F2CALCRCRHR1CRHR2NTSR2
SCHEMBL30586509 0.84 F2 (0.60) F2CALCRCRHR1CRHR2NTSR2
SCHEMBL30504289 0.84 CALCR (0.61) F2CALCRCRHR1CRHR2AGTR1
SCHEMBL31583875 0.83 NMUR2 (0.54) F2NMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115919996-A Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2023-04-07 — — CN claimed
US-20230074446-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2023-03-09 — — US claimed
US-20220331393-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2022-10-20 — — US claimed
US-11464825-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-10-11 — — US claimed
CN-107530396-B Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2022-08-26 — — CN claimed
US-11273197-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-03-15 — — US claimed
CN-109689678-B Agonist peptides for adiponectin receptors B·B·金 2024-04-09 — — CN disclosed
CN-116535469-A Peptides having adiponectin receptor agonist function and agonists of adiponectin receptor B·B·金 2023-08-04 — — CN disclosed
CN-115919996-A Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2023-04-07 — — CN disclosed
US-20230074446-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2023-03-09 — — US disclosed
US-20220331393-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2022-10-20 — — US disclosed
US-11464825-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-10-11 — — US disclosed
CN-107530396-B Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2022-08-26 — — CN disclosed
EP-4014985-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS Allysta Pharmaceuticals, Inc. (US) 2022-06-22 — — EP disclosed
US-11273197-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-03-15 — — US disclosed
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