SCHEMBL29510563

SCHEMBL29510563

CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](N)CC(N)=O)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@H](CO)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 16/20 0.58
▸ NTSR1 P30989 16/20 0.58
▸ SORT1 Q99523 14/20 0.57
▸ SLC6A2 P23975 1/20 0.57
▸ AGTR2 P50052 2/20 0.56
▸ AGTR1 P30556 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467322 0.97 OPRD1 (0.56) NTSR2NTSR1SORT1
SCHEMBL29510574 0.90 F2 (0.62) NTSR2NTSR1AGTR2AGTR1
SCHEMBL30504141 0.88 NTSR1 (0.57) NTSR2NTSR1SORT1SLC6A2AGTR2
SCHEMBL29793680 0.87 F2 (0.64) NTSR2NTSR1SORT1AGTR2AGTR1
SCHEMBL30969929 0.86 F2 (0.58) NTSR2NTSR1SORT1AGTR2AGTR1
SCHEMBL30198139 0.86 NPY1R (0.55) NTSR2NTSR1SORT1
SCHEMBL30176449 0.86 CALCR (0.60) NTSR2NTSR1SORT1
SCHEMBL29590984 0.85 NTSR2 (0.49) NTSR2NTSR1SORT1
SCHEMBL30637760 0.85 NTSR1 (0.64) NTSR2NTSR1SORT1SLC6A2AGTR2
SCHEMBL29860392 0.85 NTSR1 (0.64) NTSR2NTSR1SORT1SLC6A2AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115919996-A Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2023-04-07 — — CN claimed
US-20230074446-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2023-03-09 — — US claimed
US-20220331393-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2022-10-20 — — US claimed
US-11464825-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-10-11 — — US claimed
US-11273197-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-03-15 — — US claimed
CN-115919996-A Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2023-04-07 — — CN disclosed
US-20230074446-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2023-03-09 — — US disclosed
US-20220331393-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS ALLYSTA PHARMACEUTICALS INC (US) 2022-10-20 — — US disclosed
US-11464825-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-10-11 — — US disclosed
CN-107530396-B Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2022-08-26 — — CN disclosed
EP-4014985-A1 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS Allysta Pharmaceuticals, Inc. (US) 2022-06-22 — — EP disclosed
US-11273197-B2 Adiponectin peptidomimetics for treating ocular disorders ALLYSTA PHARMACEUTICALS, INC. (US) 2022-03-15 — — US disclosed
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