Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951068 | 0.86 | BDKRB1 (0.43) | BDKRB1 | |
| SCHEMBL3022682 | 0.74 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL3022686 | 0.67 | BDKRB1 (0.72) | BDKRB1 | |
| SCHEMBL2944571 | 0.59 | BDKRB1 (0.55) | BDKRB1 | |
| SCHEMBL3032923 | 0.58 | BDKRB1 (0.58) | BDKRB1 | |
| SCHEMBL3020770 | 0.57 | BDKRB1 (0.55) | BDKRB1 | |
| SCHEMBL14363632 | 0.54 | RAB9A (0.51) | — | |
| SCHEMBL14580440 | 0.54 | RAB9A (0.49) | — | |
| SCHEMBL14363629 | 0.54 | CASP3 (0.49) | — | |
| SCHEMBL14363614 | 0.53 | HSP90AA1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |