SCHEMBL29511728

SCHEMBL29511728

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 1/20 0.52
▸ PPARA Q07869 5/20 0.52
▸ PPARG P37231 4/20 0.52
▸ CTSS P25774 4/20 0.52
▸ CTSK P43235 3/20 0.52
▸ CTSL P07711 2/20 0.52
▸ CTSB P07858 1/20 0.52
▸ REN P00797 2/20 0.47
▸ PPARD Q03181 2/20 0.47
▸ AKT1 P31749 1/20 0.46
▸ PTPN1 P18031 2/20 0.46
▸ ITGB3 P05106 1/20 0.46
▸ ITGA2B P08514 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511604 1.00 ACE (0.52) ACEPPARAPPARGCTSSCTSK
SCHEMBL29511703 0.96 PPARG (0.56) ACEPPARAPPARGCTSSCTSK
SCHEMBL29511593 0.95 PPARG (0.48) ACEPPARAPPARGCTSSCTSK
SCHEMBL29511598 0.95 PPARG (0.48) ACEPPARAPPARGCTSSCTSK
SCHEMBL29511623 0.95 PPARG (0.49) ACEPPARAPPARGCTSSCTSK
SCHEMBL31091378 0.93 ACE (0.59) ACEPPARAPPARGCTSSCTSK
SCHEMBL23154872 0.91 CTSS (0.58) ACEPPARAPPARGCTSSCTSK
SCHEMBL30999386 0.91 CTSS (0.58) ACEPPARAPPARGCTSSCTSK
SCHEMBL9496746 0.90 PPARG (0.47) ACEPPARAPPARGCTSSCTSK
SCHEMBL9496752 0.90 PPARG (0.47) ACEPPARAPPARGCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2025-12-02 — — US disclosed
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2022-04-14 — — US disclosed
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 ACE 839/4885PPARA 798/4885PPARG 729/4885
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 ACE 836/4885PPARA 822/4885PPARG 752/4885
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 ACE 839/4885PPARA 798/4885PPARG 729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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