Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832896 | 0.90 | OPRM1 (0.47) | ACERENOPRM1OPRD1SLC6A2 | |
| SCHEMBL30444471 | 0.89 | CTSD (0.46) | ACERENSLC6A2CMA1DPP4 | |
| SCHEMBL29575785 | 0.88 | DPP4 (0.53) | ACERENOPRM1OPRD1CMA1 | |
| SCHEMBL30954023 | 0.88 | CAPN1 (0.53) | ACERENOPRM1OPRD1SLC6A2 | |
| SCHEMBL29482273 | 0.87 | CAPN1 (0.55) | OPRM1OPRD1SLC6A2CAPN1 | |
| SCHEMBL30536729 | 0.86 | OPRM1 (0.44) | ACERENOPRM1OPRD1SLC6A2 | |
| SCHEMBL7758744 | 0.85 | ACE (0.64) | ACERENDPP4FAPDPP8 | |
| SCHEMBL31126288 | 0.85 | OPRM1 (0.42) | ACERENOPRM1OPRD1CAPN1 | |
| SCHEMBL30443935 | 0.85 | CALCRL (0.46) | ACERENOPRM1SLC6A2XIAP | |
| SCHEMBL31126301 | 0.85 | CAPN1 (0.44) | ACERENOPRM1OPRD1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249816-B | Molecular design of recombinant protein medicine | 清华大学 | 2024-09-06 | — | — | CN | disclosed |
| EP-3269731-B1 | MOLECULAR DESIGN OF RECOMBINANT PROTEIN DRUG | UNIV TSINGHUA (CN) | 2023-10-04 | — | — | EP | disclosed |
| CN-114249816-A | Molecular design of recombinant protein medicine | 清华大学 | 2022-03-29 | — | — | CN | disclosed |