SCHEMBL12439592

SCHEMBL12439592

CC1(C)c2cc(N(c3ccccc3)c3cccc4ccccc34)ccc2-c2cc3c(cc21)-c1ccc(N(c2ccccc2)c2cccc4ccccc24)cc1C3(C)C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 0.39
PDK2 Q15119 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
DHFR P00374 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13907748 1.00 SIGMAR1 (0.39) SIGMAR1PDK2L3MBTL1SLC6A2SLC6A4
SCHEMBL12439779 1.00 SIGMAR1 (0.39) SIGMAR1PDK2L3MBTL1SLC6A2SLC6A4
SCHEMBL14073327 0.99 SIGMAR1 (0.38) SIGMAR1PDK2L3MBTL1SLC6A2SLC6A4
SCHEMBL4084514 0.97 SIGMAR1 (0.40) SIGMAR1PDK2L3MBTL1KDM4EMAPT
SCHEMBL17693517 0.97 SIGMAR1 (0.40) SIGMAR1PDK2L3MBTL1KDM4EMAPT
SCHEMBL29390340 0.97 SIGMAR1 (0.40) SIGMAR1PDK2L3MBTL1KDM4EMAPT
SCHEMBL29511997 0.97 SIGMAR1 (0.40) SIGMAR1PDK2L3MBTL1KDM4EMAPT
SCHEMBL14073268 0.96 SIGMAR1 (0.36) SIGMAR1PDK2L3MBTL1SLC6A2SLC6A4
SCHEMBL15138682 0.96 SIGMAR1 (0.40) SIGMAR1PDK2L3MBTL1KDM4EMAPT
SCHEMBL12640117 0.96 SIGMAR1 (0.40) SIGMAR1PDK2L3MBTL1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230058635-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20230006146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-01-05 US disclosed
US-11233201-B2 Organic electroluminescent devices and preparation methods thereof KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2022-01-25 US disclosed
US-20210143328-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed
US-10950803-B2 Compounds and uses in devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-16 US disclosed
US-10930853-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-23 US disclosed
US-10693107-B2 Organic electroluminescence device having RGB pixel areas BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) 2020-06-23 US disclosed
WO-2020108899-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-06-04 WO disclosed
US-20190319194-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-10381569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-8852756-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-07 US disclosed
US-8852756-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-07 US disclosed
US-20140239283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
EP-1860097-B1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO (JP) 2011-08-10 EP disclosed
US-20090066225-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20090066225-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20080220285-A1 Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices MERCK PATENT GMBH (DE) 2008-09-11 US disclosed
US-20080220285-A1 Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices MERCK PATENT GMBH (DE) 2008-09-11 US disclosed
EP-1860097-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080220285-A1 Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices TYR, DDT, PAH SIGMAR1 982/4885PDK2 519/4885L3MBTL1 2568/4885
US-10693107-B2 Organic electroluminescence device having RGB pixel areas RHEB, CYBA, RUVBL2 SIGMAR1 2521/4885PDK2 1551/4885L3MBTL1 783/4885
US-20230006146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD2, OCIAD1 SIGMAR1 1351/4885PDK2 3146/4885L3MBTL1 951/4885
US-20090066225-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME TYR, NLRP1, NLRP3 SIGMAR1 980/4885PDK2 953/4885L3MBTL1 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.