Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940450 | 0.86 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL13213790 | 0.85 | BDKRB1 (0.47) | BDKRB1 | |
| SCHEMBL2942746 | 0.83 | BDKRB1 (0.49) | BDKRB1FFAR1FFAR4 | |
| SCHEMBL2951261 | 0.82 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL2946397 | 0.80 | DGAT2 (0.44) | BDKRB1 | |
| SCHEMBL13214030 | 0.80 | BDKRB1 (0.69) | BDKRB1 | |
| SCHEMBL13214217 | 0.79 | DGAT2 (0.40) | BDKRB1FFAR1FFAR4 | |
| SCHEMBL2951268 | 0.78 | ALOX5AP (0.39) | BDKRB1FFAR1FFAR4LTB4R2 | |
| SCHEMBL2949484 | 0.78 | BDKRB1 (0.74) | BDKRB1 | |
| SCHEMBL13213946 | 0.76 | BDKRB1 (0.57) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |