Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29512766 | 0.98 | TSHR (0.38) | TSHRNR4A2ALDH1A1HTR2BHTR2C | |
| SCHEMBL22662669 | 0.72 | KEAP1 (0.47) | TSHRNR4A2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29512812 | 0.71 | L3MBTL3 (0.47) | ALDH1A1 | |
| SCHEMBL29931924 | 0.70 | KEAP1 (0.50) | TSHRNR4A2ALDH1A1SMN1; SMN2GLA | |
| SCHEMBL5092052 | 0.70 | KEAP1 (0.50) | TSHRNR4A2ALDH1A1SMN1; SMN2GLA | |
| Hydrochloric Acid SCHEMBL23043631 | 0.69 | KEAP1 (0.48) | TSHRNR4A2ALDH1A1SMN1; SMN2GLA | |
| Hydrochloric Acid SCHEMBL29978819 | 0.69 | KEAP1 (0.48) | TSHRNR4A2ALDH1A1SMN1; SMN2GLA | |
| SCHEMBL23043670 | 0.69 | MEN1 (0.56) | TSHRNR4A2ALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL29978530 | 0.69 | MEN1 (0.56) | TSHRNR4A2ALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL23043567 | 0.69 | NOTUM (0.46) | TSHRNR4A2ALDH1A1HTR2CNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076383-A1 | SULFONANILIDE AND BENZYLSULFONYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2022-04-14 | — | — | WO | disclosed |