Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886713 | 1.00 | POLB (0.53) | POLBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| Ammonia Solution, Strong SCHEMBL415501 | 0.98 | POLB (0.52) | POLBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL1886976 | 0.83 | POLB (0.45) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL30124712 | 0.83 | POLB (0.45) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL5746102 | 0.81 | ALDH1A1 (0.40) | POLBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL29672030 | 0.81 | NR4A2 (0.46) | POLBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL30421541 | 0.81 | ALDH1A1 (0.40) | POLBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL15894463 | 0.81 | NR4A2 (0.46) | POLBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL3208148 | 0.77 | CYP3A4 (0.37) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL31206751 | 0.77 | CYP3A4 (0.37) | POLBALDH1A1SMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |