Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25345695 | 1.00 | DGAT1 (0.41) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL29659291 | 0.85 | DGAT1 (0.38) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL30461589 | 0.85 | MTNR1A (0.37) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL25420978 | 0.85 | MTNR1A (0.37) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL20455667 | 0.85 | DGAT1 (0.38) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL25345296 | 0.82 | DGAT1 (0.36) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL29513573 | 0.82 | DGAT1 (0.36) | DGAT1PDE10ANPC1MAPT | |
| SCHEMBL25420967 | 0.81 | DGAT1 (0.43) | DGAT1PDE10AMAPT | |
| SCHEMBL30461686 | 0.81 | DGAT1 (0.43) | DGAT1PDE10AMAPT | |
| SCHEMBL25240181 | 0.81 | DGAT1 (0.38) | DGAT1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076973-A1 | 7-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |