Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22608539 | 1.00 | HAO1 (0.42) | HAO1CTRCMEN1KMT2AGAA | |
| SCHEMBL22608342 | 0.83 | HAO1 (0.50) | HAO1CTRCMEN1KMT2ACRHBP | |
| SCHEMBL22608203 | 0.83 | HAO1 (0.39) | HAO1MAPTRHEB | |
| SCHEMBL22608293 | 0.82 | ENPP2 (0.37) | HAO1HPGDF7F3ALPL | |
| SCHEMBL29490762 | 0.81 | MARS1 (0.53) | HAO1CTRCCRHBPCRHR2RHEB | |
| SCHEMBL22608406 | 0.81 | MARS1 (0.53) | HAO1CTRCCRHBPCRHR2RHEB | |
| SCHEMBL22608753 | 0.81 | MARS1 (0.47) | HAO1CTRCMEN1KMT2ACRHBP | |
| SCHEMBL29490776 | 0.81 | MARS1 (0.47) | HAO1CTRCMEN1KMT2ACRHBP | |
| SCHEMBL22608518 | 0.81 | RHEB (0.48) | HAO1RHEB | |
| SCHEMBL22815900 | 0.80 | POLB (0.42) | HAO1MAPTF7F3RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126151-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117069712-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069713-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117024420-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-114258390-A | Glycolate oxidase inhibitors for disease treatment | 生物马林药物股份有限公司 | 2022-03-29 | — | — | CN | disclosed |