Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 3/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464307 | 1.00 | KMO (0.41) | KMOXDHCHUKEIF4EPTPN5 | |
| Trifluoroacetic Acid SCHEMBL22807413 | 0.96 | KMO (0.39) | KMOXDHCHUKEIF4EPTPN5 | |
| SCHEMBL22608476 | 0.90 | HAO1 (0.37) | EIF4EHAO1 | |
| SCHEMBL22816792 | 0.87 | HAO1 (0.41) | HAO1 | |
| SCHEMBL22807414 | 0.84 | CHUK (0.35) | KMOXDHCHUKPTPN5SCN9A | |
| Trifluoroacetic Acid SCHEMBL22608670 | 0.84 | HAO1 (0.39) | HAO1 | |
| SCHEMBL23484490 | 0.81 | KMO (0.42) | KMOXDHCHUKEIF4EPTPN5 | |
| SCHEMBL23484571 | 0.80 | MARS1 (0.46) | HAO1 | |
| SCHEMBL22815937 | 0.79 | AURKA (0.46) | AKR1C2AKR1C1HAO1 | |
| SCHEMBL23294638 | 0.78 | KMO (0.48) | KMOXDHHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126151-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117069713-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069712-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117024420-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-114258390-A | Glycolate oxidase inhibitors for disease treatment | 生物马林药物股份有限公司 | 2022-03-29 | — | — | CN | disclosed |