Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359498 | 0.86 | HDAC1 (0.67) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL7996639 | 0.86 | HDAC1 (0.67) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359496 | 0.86 | HDAC1 (0.67) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359367 | 0.85 | HDAC1 (0.65) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359487 | 0.83 | HDAC1 (0.69) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359497 | 0.83 | HDAC1 (0.65) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359499 | 0.82 | HDAC1 (0.74) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL31158395 | 0.82 | HDAC1 (0.59) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359615 | 0.82 | HDAC1 (0.67) | HDAC1HDAC2HDAC6HDAC3HDAC10 | |
| SCHEMBL24359383 | 0.82 | HDAC1 (0.70) | HDAC1HDAC2HDAC6HDAC3HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087456-A1 | NEW COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |