Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30662550 | 1.00 | FOLH1 (0.50) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL30930160 | 0.93 | NOD1 (0.48) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL29350589 | 0.92 | NOD1 (0.47) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL7614754 | 0.90 | NOD1 (0.52) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL7614745 | 0.90 | NOD1 (0.52) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL30920966 | 0.88 | NOD1 (0.52) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL30964515 | 0.87 | CTSC (0.48) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL30292792 | 0.86 | PTGS1 (0.52) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL30193320 | 0.86 | FOLH1 (0.55) | FOLH1NAALAD2NOD1RIMKLAGLO1 | |
| SCHEMBL31402734 | 0.85 | NOD1 (0.46) | FOLH1NAALAD2NOD1RIMKLAGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12616761-B2 | CXCR4-targeting compounds | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-05-05 | — | — | US | claimed |
| US-20240342321-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-10-17 | — | — | US | claimed |
| US-20240100203-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-03-28 | — | — | US | claimed |
| EP-4232459-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | Provincial Health Services Authority (CA) | 2023-08-30 | — | — | EP | claimed |
| CN-116457028-A | Novel CXCR4 targeting compounds | 省卫生服务机构 | 2023-07-18 | — | — | CN | claimed |
| WO-2022082312-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2022-04-28 | — | — | WO | claimed |
| US-12616761-B2 | CXCR4-targeting compounds | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-05-05 | — | — | US | disclosed |
| US-20250242064-A1 | CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME | ALPHA-9 ONCOLOGY INC. (CA) | 2025-07-31 | — | — | US | disclosed |
| EP-4511384-A1 | CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME | Provincial Health Services Authority (CA) | 2025-02-26 | — | — | EP | disclosed |
| US-20240342321-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-10-17 | — | — | US | disclosed |
| US-20240100203-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-03-28 | — | — | US | disclosed |
| WO-2023201435-A1 | CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2023-10-26 | — | — | WO | disclosed |
| EP-4232459-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | Provincial Health Services Authority (CA) | 2023-08-30 | — | — | EP | disclosed |
| CN-116457028-A | Novel CXCR4 targeting compounds | 省卫生服务机构 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022082312-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250242064-A1 | CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME | CXCR4, CXCL12, ACKR3 | FOLH1 497/4885NAALAD2 2878/4885NOD1 1798/4885 |
| US-20240100203-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | CXCR4, CXCL12, CXCR2 | FOLH1 628/4885NAALAD2 3335/4885NOD1 2408/4885 |
| US-20240342321-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | CXCR4, CXCL12, CXCR2 | FOLH1 628/4885NAALAD2 3335/4885NOD1 2408/4885 |
| US-12616761-B2 | CXCR4-targeting compounds | CXCR4, CXCR2, CXCR3 | FOLH1 756/4885NAALAD2 1266/4885NOD1 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.