Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029589 | 0.84 | TSHR (0.61) | TSHRHSD17B10MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8887455 | 0.83 | TSHR (0.60) | TSHRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL6032715 | 0.81 | TSHR (0.55) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL29516513 | 0.80 | ALOX15 (0.63) | HSD17B10MEN1KMT2ACHRM1ALDH1A1 | |
| SCHEMBL6031094 | 0.78 | TSHR (0.52) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL16825861 | 0.77 | TSHR (0.54) | TSHRHSD17B10MEN1KMT2ACHRM1 | |
| SCHEMBL8033255 | 0.77 | SMN1; SMN2 (0.56) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL4651839 | 0.77 | SMN1; SMN2 (0.64) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10361229 | 0.77 | ALDH1A1 (0.59) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL295888 | 0.77 | SMN1; SMN2 (0.64) | TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835705-A | Heterocyclic compound and application thereof in medicine | 杭州安道药业有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-109776523-B | Heterocyclic compound and application thereof in medicine | 杭州安道药业有限公司 | 2022-04-15 | — | — | CN | disclosed |