SCHEMBL29516548

SCHEMBL29516548

CSCC[C@H](NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 10/20 0.57
▸ NTSR2 O95665 7/20 0.57
▸ SORT1 Q99523 4/20 0.57
▸ SLC6A2 P23975 1/20 0.55
▸ OPRM1 P35372 1/20 0.53
▸ OPRD1 P41143 1/20 0.53
▸ OPRK1 P41145 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30767678 0.89 CALCR (0.57) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL30767703 0.88 CALCR (0.57) NTSR1OPRM1OPRD1OPRK1
SCHEMBL31410865 0.88 SLC6A2 (0.64) NTSR1NTSR2SORT1SLC6A2OPRM1
SCHEMBL30767697 0.88 CALCR (0.59) NTSR1OPRM1OPRD1OPRK1
SCHEMBL31307249 0.87 SLC6A2 (0.66) NTSR1NTSR2SORT1SLC6A2OPRM1
SCHEMBL30767715 0.87 CALCR (0.58) NTSR1OPRM1OPRD1OPRK1
SCHEMBL30385288 0.87 NTSR1 (0.60) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL30242503 0.86 SLC6A2 (0.63) NTSR1NTSR2SORT1SLC6A2OPRM1
SCHEMBL31018327 0.85 NTSR1 (0.56) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL31410882 0.85 SLC6A2 (0.67) NTSR1NTSR2SORT1SLC6A2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
US-20230293681-A1 Antagonism of the VIP Signaling Pathway EMORY UNIVERSITY 2023-09-21 — — US disclosed
US-20230080520-A1 PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2023-03-16 — — US disclosed
US-11464855-B2 Antagonism of the VIP signaling pathway EMORY UNIVERSITY (US) 2022-10-11 — — US disclosed
US-11278595-B2 Peptides comprising non-natural amino acids and methods of making and using the same LONGEVITY BIOTECH, INC. (US) 2022-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230080520-A1 PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME APLNR, SCTR, GIPR NTSR1 13/4885NTSR2 29/4885SORT1 1229/4885
US-11278595-B2 Peptides comprising non-natural amino acids and methods of making and using the same APLNR, SCTR, GIPR NTSR1 13/4885NTSR2 29/4885SORT1 1229/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR NTSR1 18/4885NTSR2 42/4885SORT1 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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