Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19816494 | 1.00 | KDM4E (0.53) | KDM4EPKMTDP1PDE4BPDE4D | |
| SCHEMBL6341548 | 0.86 | ALDH1A1 (0.57) | KDM4ETDP1L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL28524985 | 0.83 | PRMT5 (0.41) | KDM4EPKML3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL30762140 | 0.83 | PRMT5 (0.41) | KDM4EPKML3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL21496345 | 0.81 | KDM4E (0.53) | KDM4EPKMTDP1PDE4BPDE4D | |
| SCHEMBL21942552 | 0.80 | KDM4E (0.53) | KDM4EPKMTDP1PDE4BPDE4D | |
| SCHEMBL22425204 | 0.80 | KDM4E (0.67) | KDM4EPKMTDP1PDE4BPDE4D | |
| SCHEMBL30731251 | 0.80 | KDM4E (0.67) | KDM4EPKMTDP1PDE4BPDE4D | |
| SCHEMBL23025050 | 0.80 | KDM4E (0.47) | KDM4EPKMTDP1PDE4BPDE4D | |
| SCHEMBL21942169 | 0.80 | CYP1A2 (0.44) | KDM4EL3MBTL1CYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979548-B | Compound and application thereof | 北京鼎材科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-114230573-B | Compound and application thereof | 北京鼎材科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114230573-A | Compound and application thereof | 北京鼎材科技有限公司 | 2022-03-25 | — | — | CN | disclosed |