SCHEMBL28524985

SCHEMBL28524985

Clc1nc2c(ccc3ccccc32)nc1-c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.41
PRMT3 O60678 1/20 0.41
CARM1 Q86X55 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
PRMT1 Q99873 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
PGK1 P00558 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SLC2A1 P11166 1/20 0.38
MAPT P10636 4/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
GSK3B P49841 1/20 0.37
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37
CYP3A4 P08684 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30762140 1.00 PRMT5 (0.41) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23027028 0.84 MAPT (0.41) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL19816494 0.83 KDM4E (0.53) PGK1NPC1RAB9AMAPTL3MBTL1
SCHEMBL29516865 0.83 KDM4E (0.53) PGK1NPC1RAB9AMAPTL3MBTL1
SCHEMBL21282002 0.82 KDM4E (0.58) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL29994028 0.82 KDM4E (0.58) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL31326902 0.81 TDP1 (0.50) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL19520619 0.81 TDP1 (0.50) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL21941950 0.79 KDM4E (0.54) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL30658985 0.78 KDM4E (0.41) PRMT5PRMT3CARM1EHMT2PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533912-B Compound and organic light emitting device comprising the same 株式会社LG化学 2024-01-02 CN disclosed
CN-112533912-A Compound and organic light emitting device including the same 株式会社LG化学 2021-03-19 CN disclosed