SCHEMBL29517138

SCHEMBL29517138

Oc1ccc2c(c1-c1cccc3ccccc13)CCC=C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
CYP1A2 P05177 3/20 0.36
NSD2 O96028 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.34
POLB P06746 1/20 0.33
BRD4 O60885 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
DHFR P00374 1/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
USP2 O75604 1/20 0.32
PAK1 Q13153 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GSK3B P49841 1/20 0.32
ADK P55263 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728636 1.00 MCL1 (0.36) MCL1ACMSDCYP1A2NSD2OPRM1
SCHEMBL29514531 0.79 HTR7 (0.40) POLBBRD4HSD17B10MAPTHTR1A
SCHEMBL17573430 0.77 MAPT (0.49) CYP1A2CYP2C19HSD17B10MEN1MAPT
SCHEMBL1893653 0.75 HSD17B10 (0.41) CYP1A2CYP2C9CYP2C19HSD17B10MAPT
SCHEMBL30772437 0.75 CYP1A2 (0.56) MCL1ACMSDCYP1A2NSD2OPRM1
SCHEMBL27474022 0.73 NSD2 (0.38) MCL1ACMSDCYP1A2NSD2OPRM1
SCHEMBL14233032 0.72 BCL2L1 (0.46) MCL1ACMSDCYP1A2NSD2OPRM1
SCHEMBL214870 0.71 NSD2 (0.54) MCL1ACMSDCYP1A2NSD2OPRM1
SCHEMBL29360295 0.71 NSD2 (0.54) MCL1ACMSDCYP1A2NSD2OPRM1
SCHEMBL3420267 0.71 HPRT1 (0.48) CYP1A2CYP2C9CYP2C19USP2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114471496-A Preparation method and application of multi-mode and multifunctional molecular cage high performance liquid chromatography stationary phase 济宁医学院 2022-05-13 CN disclosed